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BrdU

Introduction

Cells can naturally incorporate the thymidine analog BrdU into their cells during cell division, making this nucleoside analog an excellent marker for cell cycle and proliferation analysis. Analysis of incorporated BrdU can be with an anti-BrdU antibody.

Specifications

5-bromo-2′-deoxyuridine

Molecular formula: C₉H₁₁BrN₂O₅

Molecular weight: 307.1

CAS number: 59-14-3

Applications

Cell proliferation analysis in vitro and in vivo.

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Documents

Protocol (PDF):	A011
MSDS (PDF):	MSDS-A011
COA (PDF):	COA-A011

Reference:

A new method for introducing double-strand breaks into cellular DNA.

Limoli CL, Ward JF
Radiat Res (1993) 134:160-169

Impairment of immunological memory in the absence of MHC despite survival of memory T cells.

Kassiotis G, Garcia S, Simpson E, Stockinger B
Nat Immunol (2002) 3:244-250

Treatment with anti-LFA-1 delays the CD8+ cytotoxic-T-lymphocyte response and viral clearance in mice with primary respiratory syncytial virus infection.

Rutigliano JA, Johnson TR, Hollinger TN, Fischer JE, Aung S, Graham BS
J Virol (2004) 78:3014-3023

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