The amine-reactive 6-Oregon Green 488, succinimidyl ester can be used to create green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. This fluorinated analog of fluorescein overcomes some ...
The amine-reactive 5-Oregon Green 488, succinimidyl ester can be used to create green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. This fluorinated analog of fluorescein overcomes some ...
The amine-reactive 5(6)-Oregon Green 488, succinimidyl ester can be used to create green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. This fluorinated analog of fluorescein overcomes so...
QSY7 quencher succinimidyl ester is a nonfluorescent acceptor dye for preparation of peptide and oligonucleotide FRET probes.
Features
Fluorescence quantum yields <0.001 in aqueous solution;
Ab...
Viral RNA Lysis Buffer is intended for the isolation and purification of viral DNA/RNA from biological specimens for performance evaluation in vitro diagnostic procedures. It's compatible with commercially available...
DNAzol BD Reagent is a reagent specifically formulated for the isolation of genomic DNA from whole blood. The DNAzol BD Reagent is based on the use of a novel guanidine- detergent lysing solution which hydrolyzes RNA and all...
DNAzol Reagent is a complete and ready-to-use reagent for the isolation of genomic DNA from solid and liquid samples of animal, plant, yeast, and bacterial origin. The DNAzol Reagent is a novel guanidine-detergent lysing sol...
RNAzol BD Reagent is a ready-to-use reagent, designed to isolate total RNA, large RNA or small RNA from whole blood, plasma or serum of human or animal origin. The RNA can be used for RNA sequencing and gene expression analy...
PolyFectRNA™ Transfection Reagent is an innovative cationic nanotechnology developed specifically for the delivery of siRNA and miRNA into a wide range of eukaryotic cells. PolyFectRNA™ Transfection Reagent provi...
PolyFect™ Transfection Reagent is a biodegradable polymer based transfection reagent that forms a complex with DNA, and transports the complex into a variety of adherent and suspension cell lines. A remarkable feature ...
新型冠状病毒,也称 2019-nCoV,是一种可导致呼吸系统疾病的病毒。此病毒可引起炎症及肺 部气道内粘液和体液积聚(肺炎)。对新型冠状病毒基因结构分析从5`到3`端依次为编码复制所需的复制酶,刺突蛋白(S),小包膜蛋白(E),膜蛋白(M)和...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). SM-102 has been used in the development of lipid nanoparticles for delivery of mRNA-ba...
ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). ALC-0315 has been used in the development of lipid nanoparticles for delivery of mRN...
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons. It is a&...
DMG-PEG(2000) is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Formulations containing DMG-PEG(2000) have been used in the development of lipid ...
1,2-Distearoyl-sn-glycero-3-phosphorylcholine (DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn–1 and sn–2 positions. It has been used in combination...
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid containing 18:1 fatty acids at the sn–1 and sn–2 positions. The compound displays sensitivity towards pH change. At acid...
LNP-102 is a lipid nanoparticle (LNP) formulated with SM-102, DSPC, Cholesterol, and DMG-PEG2000. LNP-102 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
LNP-102...
LNP-0315 is a lipid nanoparticle (LNP) formulated with ALC-0315, DSPC, Cholesterol, and ALC-0159. LNP-0315 is formulated at optimal molar ratio for efficient delivery of mRNA-based vaccines.
L...
Lipid Nanoparticles (LNPs) play important role for delivery of mRNA-based vaccines.
ABP Biosciences offers a list of key lipids for formulation of Lipid Nanoparticles (LNPs).
Lipid
...
N1-Methylpseudo-UTP (N1-Methyl-Pseudouridine-5'-Triphosphate) is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenici...
Pseudo-UTP (Pseudouridine-5'-Triphosphate) is one of the most commonly used modified nucleoside-5’-O-triphosphates. Pseudo-UTP is a building block for the polymerase-mediated synthesis of RNA molecules. RNA mole...
5-Methyl-CTP (5-Methylcytidine-5'-Triphosphate) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of ...
Base modified NTPs have been widely used for synthesis of modified mRNA to improve stability and reduce immunogenicity.
ABP Biosciences offers a list of key base modified NTPs for mRNA synthesis.
C...
血管紧张素转换酶2(ACE2)是ACE的第一个同源物,它通过平衡ACE活性来调节肾素血管紧张素系统(RAS)。近年来,越来越多的证据表明ACE2在心血管,肾脏和呼吸系统中的生理和病理作用。ACE2在血压控制中也具有重要作用。该酶是ACE的同源物,水...
血管紧张素转换酶2(ACE2)是ACE的第一个同源物,它通过平衡ACE活性来调节肾素血管紧张素系统(RAS)。近年来,越来越多的证据表明ACE2在心血管,肾脏和呼吸系统中的生理和病理作用。ACE2在血压控制中也具有重要作用。该酶是ACE的同源物,水...
冠状病毒的棘突糖蛋白包含仅与宿主细胞上某些受体结合的突起。已知的结合S1的受体是ACE2,血管紧张素转换酶2,DPP4,二肽基肽酶-4,APN,氨肽酶N,CEACAM,癌胚抗原相关细胞粘附分子1,Sia,唾液酸,O-ac Sia,O-乙酰化唾液酸。峰值对于宿主...
冠状病毒的棘突糖蛋白包含仅与宿主细胞上某些受体结合的突起。已知的结合S1的受体是ACE2,血管紧张素转换酶2,DPP4,二肽基肽酶-4,APN,氨肽酶N,CEACAM,癌胚抗原相关细胞粘附分子1,Sia,唾液酸,O-ac Sia,O-乙酰化唾液酸。峰值对于宿主...
冠状病毒是具有正向 RNA 基因组且具有螺旋对称核衣壳的包膜病毒。冠状病毒核蛋白在被病 毒感染的原代细胞和被表达 N 蛋白的质粒转染的细胞中均位于细胞质和核仁(亚核结构)。 冠状病毒 N 蛋白是冠状病毒 RNA 合成所必需的,并且具有 RNA 伴...
新冠病毒核心原料
新冠病毒抗原
LNP递送磷脂
&n...
The NGS Second Strand Synthesis Module contains the enzymes and buffers required to convert first strand cDNA into double stranded cDNA. The fast, user-friendly workflow has minimal hands-on time and is compatible with upstr...
The NGS First Strand Synthesis Module contains the enzymes and buffers required to convert RNA into cDNA using random priming. The fast, user-friendly workflow has minimal hands-on time and is compatible with upstream poly(A...
The NGS Poly(A) mRNA Isolation Module is designed to isolate intact poly(A) mRNA from previously isolated total RNA. The technology is based on the coupling of Oligo d(T)25 to paramagnetic beads which is then used as the sol...
The NGS RNA Fragmentation Module is optimized to fragment RNA into small pieces using divalent cations under elevated temperature.
Applications
RNA fragmentation.
RNA Fragmentation Protocol
This protocol...
The NGS Quick Ligation Module is optimized to ligate DNA adaptors compatible with Illumina sequencing to end-repaired, dA-tailed DNA fragments. The module is optimized for use with the NGS End Repair Module (Cat #E112-1, E11...
The NGS dA-Tailing Module is used to efficiently incorporate a non-templated dAMP on the 3´ end of a blunt DNA fragment. 3´-dA DNA tailing prevents concadamer formation during subsequent ligation steps. DNA taile...
The NGS End Repair Module is used to convert 1–5 μg of fragmented DNA to blunt-ended DNA having 5´ phosphates, and 3´-hydroxyls. The module is optimized for use with the NGS dA-Tailing Module (Cat #E113-...
Klenow Fragment is a proteolytic product of E. coli DNA Polymerase I which retains polymerization and 3'→ 5' exonuclease activity, but has lost 5'→ 3' exonuclease activity. Klenow Fragment retains t...
Klenow Fragment (3'→5' exo-) is an N-terminal truncation of DNA Polymerase I which retains polymerase activity, but has lost the 5´→ 3´ exonuclease activity and has mutations (D355A, E357A) whic...
T4 Polynucleotide Kinase catalyzes the transfer and exchange of Pi from the γ position of ATP to the 5´ -hydroxyl terminus of polynucleotides (double-and single-stranded DNA and RNA) and nucleoside 3´-monop...
T4 DNA Polymerase catalyzes the synthesis of DNA in the 5’→ 3’ direction and requires the presence of template and primer. This enzyme has a 3’→ 5’ exonuclease activity which is much more ac...
Benzonase Nuclease is a genetically engineered endonuclease from Serratia marcescens. It degrades all forms of DNA and RNA (single stranded, double stranded, linear and circular) while having no proteolytic activity. It is e...
NotI-HF restriction enzyme recognizes GC^GGCCGC site and cuts best at 37°C in 5-15 minutes using Reaction Buffer provided. NotI-HF has the same specificity as native enzyme, but has been engineered for significantly redu...
Terminal transferase (TdT) is a template independent polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of DNA molecules. Protruding, recessed or blunt-ended double or single-stranded ...
ABP Biosciences 提供一系列高质量工具酶.
产品名称
货号
ABPNGS Tn5 Transposase
TN501-1/TN501-2
T4 β-Glucosyltransferase
E100-1/E100-2
T4 DNA L...
Robust dsDNA Fragmentase generates dsDNA breaks in a time-dependent manner to yield 50–1,000 bp DNA fragments depending on reaction time. Robust dsDNA Fragmentase contains two enzymes, one randomly generates nicks on d...
Blunt/TA Ligase Master Mix is a ready-to-use 2× solution, which is specifically formulated to improve ligation and transformation of both blunt-end and single-base overhang substrates. The master mix format simplifies ...
The Quick T4 DNA Ligation Kit enables ligation of cohesive end or blunt end DNA fragments in 15 minutes at room temperature.
Applications
Routine subcloning.
Recircularization of linear DNA.
Library const...
T4 DNA Ligase catalyzes the formation of a phosphodiester bond between 5’-phosphate and 3’-hydroxyl termini in duplex DNA or RNA. The enzyme repairs single-strand nicks in duplex DNA, RNA or DNA/RNA hybrids, join...
T4 β-glucosyltransferase (T4 BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that catalyzes the transfer of glucose (Glc) from uridine diphosphoglucose (UDP-Glc) to 5-hydroxymethylcytosine (5-hmC) residues in...