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6-Oregon Green 488, succinimidyl ester

Introduction

The amine-reactive 6-Oregon Green 488, succinimidyl ester can be used to create green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. This fluorinated analog of fluorescein overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range.

Specifications

Label: Oregon Green 488
Ex/Em: 496/524 nm
Detection Method: Fluorescent
Solubility: DMSO, DMF
Molecular Formula: C25H13F2NO9
Molecular Weight: 509.38
CAS Number:  
Storage Conditions: -20 ℃, protect from light
Shipping Condition: Room Temperature

Applications
Fluorescent labeling

To order

Buy Cat.No. Product name Ex/Em(nm) Size Price
C115 6-Oregon Green 488, SE 496/524 5 mg 1300

Documents

Datasheet (PDF): C115
MSDS (PDF): MSDS-C115

References:

A comparison of the emission efficiency of four common green fluorescence dyes after internalization into cancer cells.
Hama Y, Urano Y, Koyama Y, Bernardo M, Choyke PL, Kobayashi H
Bioconjug Chem (2006) 17:1426-1431.