The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial ...
The mitochondrion plays a vital role in the processes of apoptotic and necrotic cell death. The mitochondrial permeability transition pore is a nonspecific channel formed by components from the inner and outer mitochondrial ...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
Internucleosomal cleavage of DNA is a hallmark of apoptosis. DNA cleavage in apoptotic cells can be detected in situ in fixed cells or tissue sections using the terminal deoxynucleotidyl transferase (TdT) mediated dUTP nick-...
The later stages of apoptosis are characterized by changes in nuclear morphology, including DNA fragmentation, chromatin condensation, degradation of nuclear envelope, nuclear blebbing, and DNA strand break...
A distinctive feature of the early stages of apoptosis is the disruption of active mitochondria, including changes in membrane potential and alterations to redox potential. JC-1 (5,5’,6,6’-tetra...
JC-1 Mitochondrial Membrane Potential Detection Kit provides a quick and reliable method to detect the mitochondrial membrane potential changes in apoptotic cells using flow cytometry. The loss of mitochondrial membrane...
Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for caspase-3/7. It contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibitor caspase-3/7 activity in apoptotic cells, and ...
The caspase-3/7 substrate is a bisamide derivative of the fluorophore rhodamine 110 (R110). Peptides are covalently linked to each of the amino groups of rhodamine 110 (R110), thereby suppressing both the visible absorption ...
The Caspase-3/7 Z-DEVD-R110 Assay Kit provides a method for detecting apoptosis by providing a simple and reliable method for assaying caspase-3/7 activity. The kit can be used to continuously measure the activity ...
A distinctive feature of the early stages of apoptosis is the activation of caspase enzymes, which participate in the cleavage of protein substrates and in the subsequent disassembly of the cell. ABP B...
This product is provided as concentrated buffer to facilitate the binding of annexin V to phosphatidylserine for use in apoptosis assays.
Formulation: 50 mM HEPES, 700 mM NaCl, 12.5 mM CaCl2, pH 7.4.
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Andy Fluor™ 680 Annexin V is Annexin V conjugated with our far-red fluorescent dye Andy Fluor™ 680. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine ...
Andy Fluor™ 647 Annexin V is Annexin V conjugated with our red fluorescent dye Andy Fluor™ 647. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS)...
Andy Fluor™ 594 Annexin V is Annexin V conjugated with our red fluorescent dye Andy Fluor™ 594. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS)...
Andy Fluor™ 568 Annexin V is Annexin V conjugated with our red fluorescent dye Andy Fluor™ 568. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS)...
Andy Fluor™ 555 Annexin V is Annexin V conjugated with our orange fluorescent dye Andy Fluor™ 555. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (...
Andy Fluor™ 488 Annexin V is Annexin V conjugated with our green fluorescent dye Andy Fluor™ 488. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (P...
FITC Annexin V is Annexin V conjugated with our green fluorescent dye FITC. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS) to identify apoptotic cells. In norm...
Andy Fluor™ 350 Annexin V is Annexin V conjugated with our blue fluorescent dye Andy Fluor™ 350. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS) to ...
Biotin-X Annexin V is Annexin V conjugated with biotin molecule. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS) to identify apoptotic cells. In normal viable cells,...
eGFP Annexin V is Annexin V fusion tagged with green fluorescent protein eGFP. Annexin V is a calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS) to identify apoptotic cells. In normal viab...
Annexin V is a family of calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS) to identify apoptotic cells. In healthy cells, PS is predominantly located along the cytosolic side of the plasm...
Annexin V conjugates provide quick and reliable detection methods for studying the externalization of phosphatidylserine using flow cytometry or fluorescence microscopy to assess mixed populations of apopto...
Our Apoptotic, Necrotic, and Healthy Cells Detection Kit provides a convenient assay to detect apoptotic, necrotic, and total cells within the same cell population by flow cytometry or fluorescence microscopy. This kit conta...
Our FITC Annexin V and PI Apoptosis Kit is used to detect the externalization of phosphatidylserine in apoptotic cells. This kit provides a sensitive two-color assay that employs FITC annexin V and a ready-to-use solution of...
Our Andy Fluor™ 488 Annexin V and PI Apoptosis Kit is used to detect the externalization of phosphatidylserine in apoptotic cells. This kit provides a sensitive two-color assay that employs our green-fluorescent Andy F...
Our eGFP Annexin V and PI Apoptosis Kit is used to detect the externalization of phosphatidylserine in apoptotic cells. This kit provides a sensitive two-color assay that employs eGFP-annexin V and a ready-to-use solution of...
The annexin V is a 35–36 kilodalton, Ca2+-dependent phospholipid-binding protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, phosphatidylserine is located on the cyto...
细胞凋亡(Apoptosis)是指细胞为维持细胞内环境稳定,由基因控制的细胞自主的有序的死亡。细胞凋亡与细胞坏死不同,细胞凋亡不是一件被动的过程,而是主动过程,它涉及一系列基因的激活、表达以及调控等的作用,它并不是病理条件下...