PKH67 Green Cell Membrane Labeling Kit

PKH67 is a green‐fluorescent dye. This lipophilic membrane dye is widely used for cytotoxicity assays.

PKH67 Green Cell Membrane Labeling Kit is used for general cell membrane labeling. It has proven useful for monitoring exosome or liposome uptake, cell-cell membrane transfer, phagocytosis, and antigen presentation as well as for in vivo cell trafficking studies.

Correlation of in vitro cell membrane retention with in vivo rate of intensity decrease in non-dividing cells predicts an in vivo fluorescence half-life for PKH67 of 10-12 days. PKH67 is therefore recommended for short-to-medium term in vivo studies requiring a green cell linker dye, as well as for in vitro cytotoxicity, phagocytosis, proliferation, antigen presentation, or other co-culture assays. Due to its extremely stable fluorescence, PKH26 remains the cell linker dye of choice for longer term in vivo studies in which labeled cells are to be followed for periods longer than a few weeks.

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