CDCFDA

Introduction

5(6)-CDCFDA is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activity, which is require to activate its fluorescence, and cell-membrane integrity, which is required for intracellular retention of their fluorescent product. Upon hydrolysis by intracellular esterases, the 5(6)-CDCFDA yields the fluorescent fluorophore, 5-(and-6)-carboxy-2',7' -dichlorofluorescein. With a pKa of 4.8, this dye can be used as an acidic pH sensor.

Specifications:     
Excitation/Emission: 504/529 nm (after cleavage)
Shipping Condition: Ambient
Storage Conditions: -20ºC, protect from light
Molecular Formula: C25H14Cl2O9
Molecular Weight: 529.29
CAS Number: 127770-45-0  

 

To Order

Buy Cat.No. Product name Ex/Em(nm) Size Price
C035 CDCFDA 504/529 100 mg 800

Documents

Protocol (PDF): C035
MSDS (PDF):  MSDS-C035
COA (PDF):  C035